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The NMF is responsible for hydration, a strong barrier, and plasticity
It neutralizes the stomach acid long enough for the GLP-1 to be absorbed into the bloodstream, retaining higher bioavailability, though still not as high as injectable GLP-1s
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The most pronounced change in the GSH/(GSH+GSSG) ratio is observed after 1 hour treatment at 37C (from 87% to 73%) (Figure 2), partially reflecting the observed roGFP oxidation (Figure 1B)